The Nifty® Test
The World’s Leading Non-Invasive Prenatal Test (NIPT)

Who Can Be Screened With Nifty® ?

  • Pregnant mother at every age
  • Singleton or twin pregnancy and surrogate mother
  • Received IVF Treatment
  • Concerned about the risk of amniocentesis
  • Fetal ultrasonographic findings have indicated an increased risk of aneuploidy
  • History of a prior pregnancy with a trisomy
Group 426

12M+

Families worldwide
choose NIFTY®

Group 423

10

Available from 10th gestational
week with 10ml maternal blood

Group 425

>99%

Accuracy for detecting
Down syndrome

Group 427

7-10

Report delivered within
7-10 working days

Group 424

0%

Non-invasive with no
risk of miscarriage

Group 422

147,000

Largest clinical validation to date
with nearly 147,000 pregnancies

Package Test Options

Pro-1
Trisomies
Trisomy 21 (Down Syndrome)
Trisomy 18 (Edwards Symdrome)
Trisomy 13 (Patau Syndrome)
Gender Identification
Male / Female
Trisomies
Trisomy 9
Trisomy 16
Trisomy 22
Other Trisomies
Sex Chromosome Aneuploidies
Monosomy X (Turner syndrome)
XXY (Klinefelter syndrome)
XXX (Triple-X)
XYY (Jacob’s syndrome)
Deletion / Duplication
84 kinds of microdeletion / duplication
core-1
Trisomies
Trisomy 21 (Down Syndrome)
Trisomy 18 (Edwards Symdrome)
Trisomy 13 (Patau Syndrome)
Gender Identification
Male / Female
Trisomies
Trisomy 9
Trisomy 16
Trisomy 22
Other Trisomies
Sex Chromosome Aneuploidies
Monosomy X (Turner syndrome)
XXY (Klinefelter syndrome)
XXX (Triple-X)
XYY (Jacob’s syndrome)
Focus -1
Trisomies
Trisomy 21 (Down Syndrome)
Trisomy 18 (Edwards Symdrome)
Trisomy 13 (Patau Syndrome)
Gender Identification
Male / Female
Sex Chromosome Aneuploidies
Monosomy X (Turner syndrome)
XXY (Klinefelter syndrome)
XXX (Triple-X)
XYY (Jacob’s syndrome)
Twin-1
Trisomies
Trisomy 21 (Down Syndrome)
Trisomy 18 (Edwards Symdrome)
Trisomy 13 (Patau Syndrome)
Y Chromosome

Package Test Options

Mask Group 34

Trisomies

 Trisomy 21 (Down Syndrome)

 Trisomy 18 (Edwards Symdrome)

 Trisomy 13 (Patau Syndrome)

 Trisomy 9

 Trisomy 16

 Trisomy 22

 Other trisomies

Gender Identification

 Male / Female

Sex Chromosome Aneuploidies

 Monosomy X (Turner syndrome)

  Trisomy 18 (Edwards Symdrome)

XXX (Triple-X)

XXY (Jacob’s syndrome)

Microdeletion / Duplication

84 kinds of microdelectiom / duplication

Mask Group 34

Trisomies

 Trisomy 21 (Down Syndrome)

 Trisomy 18 (Edwards Symdrome)

 Trisomy 13 (Patau Syndrome)

 Trisomy 9

 Trisomy 16

 Trisomy 22

 Other trisomies

Gender Identification

 Male / Female

Sex Chromosome Aneuploidies

 Monosomy X (Turner syndrome)

  Trisomy 18 (Edwards Symdrome)

XXX (Triple-X)

XXY (Jacob’s syndrome)

Mask Group 32

Trisomies

 Trisomy 21 (Down Syndrome)

 Trisomy 18 (Edwards Symdrome)

 Trisomy 13 (Patau Syndrome)

Gender Identification

 Male / Female

Sex Chromosome Aneuploidies

 Monosomy X (Turner syndrome)

 Trisomy 18 (Edwards Symdrome)

XXX (Triple-X)

XXY (Jacob’s syndrome)

Mask Group 33

Trisomies

 Trisomy 21 (Down Syndrome)

 Trisomy 18 (Edwards Symdrome)

 Trisomy 13 (Patau Syndrome)

Y Chromosome

A Comparison of Detection Rates

  • Available from week 10

    0%
  • Serum Integrated Screening Available from week 15

    0%
  • Quad Screening Available from week 15

    0%
  • First Trimester Screening Available from week 10

    0%

Workflow

test

STEP 1

Physician orders test

test-tube

STEP 2

8-10 mL blood sample collected

truck

STEP 3

Sample shipped to BGI & analyzed

stethoscope

STEP 4

Results sent in 7-10 working days

Knowledge

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Under 35

Did you know? Pregnant woman under 35 years are at risk for having an infant with Down syndrome. In Thailand, there are approximately 800,000 pregnant women in each year. From this number, infant with down syndrome is accounted for 800-1,000 persons. Since 2004, the Ministry of Public Health (MOPH) has recommended that pregnant women aged over 35 years must engage to the chromosome abnormalities testing in newborn, due to advance maternal age is related to higher risk in Down syndrome. However, the statistics of children with down syndrome reveals that 75-80 % are born from woman younger than 35 years.

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“Trisomy” Genetic disease with no cure

The genetic information passed from parent to child. Thus, any changing of genes might be passed which cause of genetic disease in their child. Until now, these genetic diseases cannot be cured. Thus, treatment strategies are designed to improve signs and symptoms that associated with disorder Down syndrome is one of genetic disease. The major cause might not be passing on the gene but cause of other factors such as age of mother, mother’s egg abnormalities. Down syndrome is also known as Trisomy 21, because the alteration in the number or genetic structure of chromosome 21. The incidence at birth of Trisomy 21 is 1:800.

Publications

Publications
Zhang, H., et al. (2015). Non-invasive prenatal testing for trisomies 21, 18 and 13: clinical experience from 146,958 pregnancies. Ultrasound Obstet Gynecol, 45(5), 530-538. doi: 10.1002/uog.14792
Lau, T. K., el at. (2013). Non-invasive prenatal screening of fetal Down syndrome by maternal plasma DNA sequencing in twin pregnancies. The Journal of Maternal-Fetal and Neonatal Medicine 2013 Mar;26(4): 434-7

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